LIFT & FILL CREAM

Item number: idlafcrm

Ideal to reduce wrinkles, lift, firm and rejuvenate the skin. Dermatologically tested, suitable for sensitive skin, SPF20.

24,95 €
49,90 € per 100 ml

including19% VAT., plus shipping (Post)

Recommended retail price: 29,95 €
(You save 16.69%, that is 5,00 €)
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Description

This cream provides a real cocktail of effective natural ingredients to the skin, which nourishes and tonifies the skin.

  • With Youth Genes Activator, hyaluronic acid in high concentration, UVA/UVB filters, ...
  • Dermatologically tested, suitable for sensitive skin.
  • It offers a medium sun protection (UVA + UVB SPF 20) to prevent the signs of photoaging of the skin.
  • Its nutritious texture, provides comfort and well-being to dry skins.

Its unique anti-aging formula contains hyaluronic acid in high concentration (in low as high molecular weight), a natural component of the skin, and whose content is diminished over the years. This penetrates the skin, captures water increases its volume, filling the wrinkles.
At the same time, it has organic silicon &Matrigenics 14G (a youth gene activator, an anti-aging active that acts through the reactivation of 14 genes involved in the synthesis of collagen, elastin and hyaluronic acid).
Ideal in combination with IDEALDERM lifting & firming serum.

Key active ingredients:
its unique anti-aging formula contains:

  • Hyaluronic acid in high concentration (Low & High Molecular Weight).
  • 2% Matrigenics 14G, an anti-aging active, that acts through the reactivation of 14 genes involved in the synthesis of collagen, elastin and hyaluronic acid.
  • 1% Organic silicon
  • Vitamine E
  • ...

Presentation:
50ml / 1.69 fl oz Jar.





Matrigenics 14G, an anti-aging active, that acts through the reactivation of 14 genes involved in the synthesis of collagen, elastin and hyaluronic acid.

Restructuring extra cellular matrix to reduce wrinkles


With age, negative expressions have a tendency to become set as the skin loses its elasticity, and positive expressions lose their structure as the skin starts to sag. While crow's feet are considered as being smile wrinkles, forehead lines on the other hand harden the gaze. Deeper and deeper, nasal furrows with the appearance of circumoral wrinkles indicate bitterness.

triangle of beauty


In young women, high cheekbones and a tapering chin form what is called a triangle of beauty. In older women, forehead lines and nasal furrows delineate an inverse triangle of beauty (Fig. 1).

Natural ageing of the skin is the result of a slow, progressive and genetically determined process. With age, the genes that code for the synthesis of the dermal structural molecules- elastin, collagen and hyaluronic acid- enter a "sleeping phase". The dermal matrix loses its structure and the skin loses its firmness, fixing in long term lines and accentuating wrinkles.

To fight this genetically programmed inversion of the triangle of beauty, Codif Recherche et Nature has developed an extract of fertile bases of Undaria pinnatifida called Matrigenics.14 G. This new active ingredient is rich in wakamic ester. Its activity is to reactivate genes that have gone to sleep.

Undaria pinnatifida
Undaria pinnatifida, also called wakame, is a brown macro-alga from Asia where it is grown on ropes and then eaten. It has been introduced into a large number of areas all around the world, either by ships or with Japanese oyster spat. Codif Recherche et Nature cultivates wakame in a protected area of the Rance estuary (Brittany- France) on a system of submerged ropes.

Undaria pinnatifida (wakame)
Figure 2

The blade of Undaria pinnatifida is denticulated with a central nerve running through it. The stipe is flat. At maturity, the edges of the stipe widen and become wavy (Fig. 2). These new tissues called fertile bases or mekabu contain the spores by which the species is able to reproduce.

When released into the sea, the spores swim to a rocky substrate where they attach themselves and germinate to create a new alga. The fertile bases represent a concentration of life that not only ensures the reproduction of the algae but its survival across the centuries. To assess the benefit of these fertile bases for ageing skin, Codif Recherche et Nature isolated them from the rest of the alga to extract their compounds. Their laboratory has discovered a sulphated galactofucan called wakamic ester. This new molecule is able to activate the genes involved in the synthesis and organisation of the main components of the extra cellular matrix: collagen, elastin and proteoglycans.

Fourteen genes involved in restructuring the dermal matrix reactivated!
The effect of Matrigenics.14 G (now referred to as "the Undaria pinnatifida extract") on the gene's expression of the extra-cellular matrix has been evaluated on human dermal fibroblasts cultivated with 2% of active ingredient for 24 hours. The gene analysis has been carried on using DNA arrays.

The Undaria pinnatifida extract reactivates genes linked to collagen expression (Fig. 3).
The Undaria pinnatifida extract stimulates the expression of proteins involved in collagen maturation such as:
- Prolyl 4-hydroxylase P4HA1 (+61%) and P4HA2 (+30%): which both have an effect on the early stage of posttranslational collagen modification.
-Lysyl oxydase LOX (+50%) and Lysyl oxydase-like 2 LOXL2 (+43%): which have an effect on a later stage of collagen synthesis.

ractive les gnes lis  l'expression du collagne
Figure 3

In addition it stimulates the expression of:
- Collagen 1 (alpha chain 1) by +15% (effect illustrated in Figure 4). Collagen 4 (alpha chain 2) by +20%.
-Collagen 8 by +37% which is a FACIT (fibril-associated collagens with interrupted triple helices) which binds fibres to their environment.
-Lumican (LUM) by +72%, which is a proteoglycan of the SLRP (small leucine-rich proteoglycan) family which binds to collagen fibres to control their organisation (the space between fibres).
-Decorin (DCN) by +23%, which is also a proteoglycan of the SLRP (small leucine-rich proteoglycan) family which binds to collagen fibres.

Collagne Lumican Decorin
Figure 4

The Undaria pinnatifida extract reactivates genes linked to elastic fibre expression (Fig. 5).

Undaria pinnatifida ractive les gnes lis  l'expression des fibres lastiques
figure 5

The Undaria pinnatifida extract stimulates the expression of several genes involved in elastin synthesis and maturation such as:
-Elastin by +21% (effect illustrated in Figure 6).
-Fibrillin 1 by +36%, which participates in elastic fibre maturation.
- Lysyl oxydase LOX by +50% and Lysyl oxydase-like 2 LOXL2 by +43%; both of these are involved in elastin maturation.
-TIMP2 by +18%, which inhibits gelatinase A (or MMP2) activity, which breaks down elastin (elastolysis).

maturation de l'lastine
figure 6
The Undaria pinnatifida extract reactivates genes linked to hyaluronic acid expression.
The Undaria pinnatifida extract also stimulates expression of genes involved in the synthesis and the activity of hyaluronic acid such as:
-Hyaluronan synthase HAS2 (by +68%), this is the enzyme which synthesises hyaluronic acid.
-Hyaluronate receptor CD44 (by +31%), which is a receptor for hyaluronic acid which promotes cellular migration.

In vivo evaluation of the anti-ageing effect of the Undaria pinnatifida extract
The anti-ageing effect of the Undaria pinnatifida extract was measured using a new fringes projection technology named Face Scanner III-EO, recently developed by the company Eotech (Marcoussis, France). This technology uses the technique of fringes projection with 180 configuration. The machine can assess the signs of facial ageing in 3D.

The Undaria pinnatifida extract was tested at 2% in a cream against a placebo, by two panels of 22 volunteers, applying the product twice a day. The effect of the Undaria pinnatifida extract on forehead lines, nasal furrows and circumoral wrinkles was evaluated after 14 and 28 days of treatment. Average results are presented in Figure 7, with data expressed versus placebo.

crme  2% d'Undaria pinnatifida
figure 7

Effect on the forehead lines
After 14 days of application the Undaria pinnatifida extract significantly reduces the volume (-23.8%) and the area (-14.4%) of forehead lines (Fig. 8). It reduces them by 17% and 12% after 28 days.

Effet sur les lignes frontales
figure 8

Effect on the nasal furrows
The volume and area of nasal furrows are reduced by 2% and 6% respectively after 14 days and by 8% and 9% after 28 days (Fig. 9).

Effet sur les sillons nasaux
figure 9

Effect on the circumoral wrinkles
The Undaria pinnatifida extract reduces the volume and area of circumoral wrinkles by 3% and 4% after 14 days and by 18% and 16% after 28 days.

Conclusion
Thanks to its richness in Wakamic ester, Matrigenics.14 G activates 14 genes involved in the synthesis of the main components of extra cellular matrix: collagen, elastin and hyaluronic acid.
In only 14 days Matrigenics.14 G restructures the dermis and reduces wrinkles volume and area, thus acting against inversion of the triangle of beauty and the accentuation of negative expressions.


Skin type: All Skin Types normal skin mature skin dry skin combination skin sensitive skin
Skin Condition: Anti-Aging Wrinkles Dull skin Tired & sagging skin Aging Skin
Area of application: Face Neck Cleavage
Consistency: cream
Sun Protection Factor : SPF 20
Main active ingredients: Silicium Vitamin E Hyaluronic acid Matrigenics 14G
Product weight: 0,05 Kg
Contents: 50,00 ml
Ingredients: Aqua, Dimethicone, Octocrylene, Dibutyl Adipate, Glycerin, C12-15 Alkyl Benzoate, 4-Methylbenzylidene Camphor, Squalane, Butyl Methoxydibenzoylmethane, Pentaerythrityl Distearate, Aluminum Starch Octenylsuccinate, Cetyl Alcohol, Glyceryl Stearate, Methylpropanediol, Titanium Dioxide (Nano), Methylsilanol Mannuronate, Sodium Hyaluronate, Undaria Pinnatifida Extract, PEG-75 Stearate, Caprylyl Glycol, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Tocopheryl Acetate, Phenoxyethanol, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (Nano), Ceteth-20, Steareth-20, Carbomer, Silica, Parfum, Disodium EDTA, Phenylpropanol, Decyl, Glucoside, Sodium Hydroxide, Ethylhexylglycerin, Hexyl Cinnamal, Benzyl Salicylate, Butylphenyl Methylpropional, Alpha-Isomethyl Ionone, Citric Acid, Citronellol, Linalool, Limonene, Geraniol, Propylene Glycol, Xanthan Gum, Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Sorbic Acid.
Usage instructions: Morning after cleaning apply generously on your face, neck and dcollet. Avoid contact with eyes. Ideal in combination with IDEALDERM lifting & firming serum (reduces sagging, increases firmness and improves the elasticity of the skin for a long period of time. Reduces and smoothes wrinkles and lifts the face).
Bewertungen:
  • Endlich die richtige Tagescreme gefunden!
    am 10. September 2018
    Habe schon mehrere Produkte von Idealderm gekauft. Von der Peelinglotion bin ich total begeistert. Mein letzter Kauf war die Lift und Fill Lifting Gesichtscreme. Das Produkt lsst sich gut verteilen und zieht rasch ein.Was mir sehr wichtig ist ,da ich sofort Make up auftragen kann. Gut gefaellt mir,dass die Creme IST 20 enthaelt.
  • von jm
    sehr schnelle Lieferung - alles prima - vielen Dank und gerne wieder
  • Endlich glcklich
    Von Andrea Ec*****n am 12. Februar 2018
    Ich habe eine sehr sensible Haut, doch bei idealderm habe ich endlich Produkte gefunden, mit denen ich sehr zufrieden bin. Meine Haut fhlt sich weich an u sieht frisch u ausgeruht aus . Ich bleibe bei diesen Produkten.

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